Dr. Matthew Budoff presented data on December 9, 2023, demonstrating that a subgroup of individuals with very high total cholesterol and LDL do not seem to develop heart disease. The subjects are known as "Lean Mass Hyper Responders." The group became notable during the rise in popularity of ketogenic diets. This post will cover what a ketogenic diet is, what a lean mass hyper responder is, the possible mechanism of why they seem to be immune to heart disease, and the study itself.
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