Posts tagged 125
The Vitamin D, Statin, and Cholesterol Paradox

The major precursor of vitamin D is cholesterol. Without cholesterol, we cannot make it. Some people may find this shocking because vitamin D is highly praised, while cholesterol is demonized. Since vitamin D and cholesterol are so closely related, they have an interesting interplay. Statin drugs, which lower cholesterol, also take part in the interplay. The enzyme statins block is active at step two, so we would expect less production of all molecules in the cholesterol pathway, like CoQ10. Statins should block vitamin D production, but they don’t. Statins are supposed to lower your risk of heart disease. But by how much? You may be surprised by the answer. This post will cover the synthesis of cholesterol, vitamin D, and Co Q10 and discuss how statins alter the pathways.

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