Stop the Cholesterol Madness

After repeated conversations with me, a close relative in his late 50s decided to try the carnivore diet. He immediately began to feel better than he had ever felt. The carnivore diet is ultra-low-carb, similar to the ketogenic diet, which often raises LDL and total cholesterol. He has lost 22 pounds, lowered his BMI from 25.8 (overweight) to 22.8 (normal), lowered his blood pressure from 110/70 to 100/66, has more energy, lowered his triglycerides from 106 to 71 (lower is better), raised his HDL from 47 to 79 (higher is better), lowered his VLDL by 1/3, rid himself of chronic foot and hip pain, and he has no more leg cramping. As we will see later in this post, these changes indicate inflammatory, metabolic, and cardiovascular health improvements.

At the same time, he raised his LDL from 69 to 192 and his total cholesterol from 137 to 285, which made his doctors panic. Later in this post, we will see that LDL levels below 105 cause twice the amount of death. Despite this, his doctors have ignored nine positive changes and stressed two that, as we will see in this post, have little relevance in their ability to predict cardiovascular disease. What kind of a world do we live in when doctors fret when their patients become healthier? Read on if you are curious.

The Vitamin D, Statin, and Cholesterol Paradox

The major precursor of vitamin D is cholesterol. Without cholesterol, we cannot make it. Some people may find this shocking because vitamin D is highly praised, while cholesterol is demonized. Since vitamin D and cholesterol are so closely related, they have an interesting interplay. Statin drugs, which lower cholesterol, also take part in the interplay. The enzyme statins block is active at step two, so we would expect less production of all molecules in the cholesterol pathway, like CoQ10. Statins should block vitamin D production, but they don’t. Statins are supposed to lower your risk of heart disease. But by how much? You may be surprised by the answer. This post will cover the synthesis of cholesterol, vitamin D, and Co Q10 and discuss how statins alter the pathways.