Posts tagged Statin
The Cognitive Dissonance of Cholesterol and Oreos

Cognitive dissonance is a psychological phenomenon that occurs when a person holds two contradictory beliefs at the same time. The psychologist Leon Festinger came up with the concept in 1957. Festinger believed that all people are motivated to avoid or resolve cognitive dissonance due to the discomfort it causes, and it can prompt people to adopt certain defense mechanisms when they have to confront it—namely, avoidance, delegitimizing, and limiting the impact. The last thing people seem to want to do is confront the conflicting ideas and change their beliefs. Sadly, scientists are not immune to this phenomenon. Today I am going to present some recent studies that are generating cognitive dissonance even though they do a better job of explaining phenomena related to cholesterol levels than the traditional theories.

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Stop the Cholesterol Madness

After repeated conversations with me, a close relative in his late 50s decided to try the carnivore diet. He immediately began to feel better than he had ever felt. The carnivore diet is ultra-low-carb, similar to the ketogenic diet, which often raises LDL and total cholesterol. He has lost 22 pounds, lowered his BMI from 25.8 (overweight) to 22.8 (normal), lowered his blood pressure from 110/70 to 100/66, has more energy, lowered his triglycerides from 106 to 71 (lower is better), raised his HDL from 47 to 79 (higher is better), lowered his VLDL by 1/3, rid himself of chronic foot and hip pain, and he has no more leg cramping. As we will see later in this post, these changes indicate inflammatory, metabolic, and cardiovascular health improvements. 

At the same time, he raised his LDL from 69 to 192 and his total cholesterol from 137 to 285, which made his doctors panic. Later in this post, we will see that LDL levels below 105 cause twice the amount of death. Despite this, his doctors have ignored nine positive changes and stressed two that, as we will see in this post, have little relevance in their ability to predict cardiovascular disease. What kind of a world do we live in when doctors fret when their patients become healthier? Read on if you are curious.

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NNT: Your Defense Against Modern Pharmaceutical Snake Oil Sales Tactics

Many popular pharmaceuticals are presented as miraculous cures when, in fact, they have much lower effectiveness than the sellers claim. As a result, most of us believe most medicines to be far more potent than they are and assume they have fewer side effects than in reality. We may be more likely to accept a prescription than not, by default, based more on faith in the results than the true knowledge of their effectiveness.  The term "Snake Oil" refers to a medical solution that is promoted as a cure-all for various illnesses but is fake and worthless. A snake oil salesman sells these useless products for a quick profit and then escapes to avoid the consequences. Many of these were salespeople who traveled from place to place selling their goods. Regrettably, these individuals frequently focused on vulnerable groups such as the elderly and those who are unwell. Some things never change. You may have noticed the numerous medication ads and cover stories on the news that make them sound so wonderful. Are the medications as effective as they say? The answer is, sadly, usually no. How did they get away with this? Read on to find out.

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The Vitamin D, Statin, and Cholesterol Paradox

The major precursor of vitamin D is cholesterol. Without cholesterol, we cannot make it. Some people may find this shocking because vitamin D is highly praised, while cholesterol is demonized. Since vitamin D and cholesterol are so closely related, they have an interesting interplay. Statin drugs, which lower cholesterol, also take part in the interplay. The enzyme statins block is active at step two, so we would expect less production of all molecules in the cholesterol pathway, like CoQ10. Statins should block vitamin D production, but they don’t. Statins are supposed to lower your risk of heart disease. But by how much? You may be surprised by the answer. This post will cover the synthesis of cholesterol, vitamin D, and Co Q10 and discuss how statins alter the pathways.

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Should You Be Taking CoQ10?

Coenzyme Q10 has two main functions. Most importantly, it helps us make ATP, our energy source for life. Since it is critical for energy production, it is most abundant in heart muscle, pancreas tissue, the brain, and the liver. The other function is to increase some of our essential antioxidants and act as one. Many factors can contribute to CoQ10 deficiency. These are aging, disease, dietary deficiency, statin drugs, and increasing tissue demands. Although our bodies make it, it is easy to get from foods, it is one of the more popular supplements available today because evidence shows it is beneficial for our health. This post will cover what it is, what it does for us, and how you can maintain adequate levels.

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