Recent studies have shown that insulin is not only important for regulating glucose levels, but also plays a significant role in maintaining healthy mitochondria, particularly in terms of fission. New research suggests that insulin spikes, which often occur after consuming processed carbohydrates, can increase the activity of two substances, RalA and Drp1, leading to the fragmentation of mitochondria. This process highlights a key mechanism through which dietary choices can impact metabolic health and the risk of obesity. This post will cover the mechanism and what we can do to avoid damaging our mitochondria.
Read MoreMany traditional ways of measuring your risk for having a heart attack are not nearly as accurate as many believe. For example, many believe that our total cholesterol and LDL are the best indicators for heart disease, but the association is weak. As far back as 1964, Garrett, Horning, and Creech found no definite correlation between serum cholesterol levels and the nature and extent of atherosclerotic disease. They published their findings in the Journal of the American Medical Association. The famous Framingham heart study concluded in 1977 that HDL was a much better predictor of heart disease than LDL, and total cholesterol was not associated with any risk. In 1997, The Lancet published a paper on the elderly that showed for each 18 mg/dl increase of cholesterol, the chance of death went down by 15%. Amazingly, they also found that mortality from cancer and infection was significantly lower among the participants in the highest total cholesterol category. We believe these readings to be the best way to predict heart disease because we have been told to. Today I will show you some more statistical hocus pocus that helped promote these tests, and tell you about a much more accurate one you should get.
Read MoreThe most effective treatment for chronic conditions is diet and lifestyle intervention, which help restore normal hormonal and metabolic function. Even mildly abnormal glucose levels are an early warning sign for many chronic conditions, such as insulin resistance, diabetes, metabolic syndrome, mitochondrial health, blood vessel damage, heart disease, strokes, and brain health. Blood glucose measurements are one of the best ways to assess metabolic function and overall health. A fasting blood glucose test and the hemoglobin A1c level are two of the most common measurements doctors look at to evaluate your metabolism. Both of these measurements have limitations. Because they are one-time measurements, they fail to consider the bigger picture, miss fundamental problems, and are unreliable (specifically a1c). A better way to understand the dynamic nature of our blood glucose is a continuous glucose monitor, also called a CGM. In this post, I will l talk about the many benefits to using one.
Read MoreInsulin promotes the uptake of glucose by cells and its storage as glycogen. The insulin and glucose tend to balance out in healthy individuals. In healthy individuals, our cells readily respond to insulin and quickly take up glucose. In many people the body produces insulin, but it is not enough to effectively keep up, and blood sugar rises. Most doctors focus on reading blood sugar levels to diagnose health problems. It turns out that high insulin levels precede high sugar levels, making it an excellent predictive test for disease.
Read MoreThe combination of obesity, specific heart-health markers, and some metabolic measurements are collectively known as metabolic syndrome. Essentially our metabolism has a direct impact on our overall health and heart health specifically. The health implications are dire, not just for our cardiovascular systems. With Covid-19, obesity is strongly associated with increased severity of COVID-19 infections, even in the absence of other underlying health issues. In this post, I have included an interactive guide to all of the steps you need to include to improve your looks, mood, and energy level. Your "body composition" will take care of itself as you focus on the things listed in the guide. Best of all, your chances of dying from disease and infection will diminish.
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